You are talking about the Asus Eee PC right? (This: http://www.asus.com/Eee/Eee_PC/Eee_PC_1000/)
If so I think you default is Xandros in a "simpel mode" with very big icons.
(something like this: http://www.pisitoenmadrid.com/blog/wp-content/uploads/2008/02/asus_eee_xandros.jpg)
You can read about it here:
Myself has an Asus 701 4G Linux and switched for advanced/normal/full desktop the first thing. I have been thinking about changing distro. on it for a long time now.
There is a lot of notebook Linux distributions and a lot of users upgrade to things like:
It's quite easy to test these out, you can download iso and put them on a usb stick and live boot them as whit CD's to test whiteout installing/changing your current system.
This tool is one commonly used for that: http://sourceforge.net/projects/unetbootin/
To say Linux don't have virus is not right. (that most users don't have to care because all of them is patched with updates maybe is) See http://en.wikipedia.org/wiki/Linux_malware#Viruses
You also have list of antivirus for linux on the same page, but you can be safe without it in my opinion.
Hope that was to some help for you.