We have developed an application in the MATLAB environment to apply statistical analysis to large ( ie: 200+ GB ) data sets. This application is a freely distributed research tool in the neuroscience field.
We have encountered a problem with the Linux ( and Mac ) kernel caching capacity. In the MATLAB environment, prior to allocating memory in variable space, the application determines if there is sufficient contiguous available memory, and returns an error if not. To ensure safety, only available memory is checked, and the kernel cache, though available, is disregarded.
During several phases of the processing, data is read from and written to disk multiple times. This consumes the kernel cache at an average rate of 500MB per operation, and quickly caches 20+GB on my test workstation, causing the application to return an 'out of memory' error (even though the cached memory is still available).
While I have operated in the past using various cache clearing operations ( such as sudo echo 3 | tee /proc/sys/vm/drop_caches ), this is not an entirely desirable option for distribution for several reasons.
1) not all potential users may be on the sudoers list
2) not all distributions will allow permissions to a sudo user for this operation
3) even if a sudo works, some operations may take as much as an hour to conclude, making it paramount for the researcher to be available to re-enter the password. As a full analysis may take 16-20 hours, this is not a feasible option.
What I think is needed is an ability to turn off or otherwise limit the kernel caching on an as needed basis. So far, I have found no options for this, other than rebuilding the kernel, an option most labs will not have available.
I will also be discussing this issue with the MATLAB developers team, though a proper resolution for public distribution may require action from both ends ( as well as ours ).
The manual released to the researcher community discusses this issue in depth, and offers some temporary mitigations, but it is quite inadequate to a full multi pass analysis. Additionally, while neuroscience researchers are quite brilliant in their own field, some aspects of computing just seem to fall short of comprehension to them.