Unfortunately, Photoshop hasn't worked well under Wine since version 7 (pre-CS5). I still keep that version on my system, but to tell the truth I usually run such applications in a Windows virtual machine running under Linux. If you want to run CS6 (or 5 for that matter), then you will have to pay the Microsoft tax... :-( Open source alternatives? Try GIMP. The latest versions have been well-received by the graphics arts community. As for animation tools, there are good FOSS tools for that as well. I'll check with my sister-in-law (a professional animator and animation educator) to see what she knows about FOSS tools of the trade.